Algorome | Multi-Omics Intelligence

// MISSION STATEMENT

Interpreting the
complexity of Human Biology.

Genomics is not just about reading code; it's about understanding context. Algorome integrates transcriptomic layers with standard NGS data to reduce ambiguity in variant classification.

Our platform provides clinicians and researchers with high-confidence decision support, moving beyond simple pattern matching to structural causality.

Clinical Modules

Specialized workflows for diagnostic challenges.

Counselor Assistant

Automate the triage of Variants of Uncertain Significance (VUS) with phenotype-driven prioritization. Our tool generates ACMG-compliant reports ready for clinical review.

Automated literature mining for rare variants.
Inheritance pattern visualization (Pedigree integration).
Patient-friendly report summaries.

[ INTERFACE PREVIEW ]

STATUS: VUS -> LIKELY BENIGN
CADD Score: 12.4 | AF: 0.05%

Polygenic Risk & Severity

Move beyond binary diagnosis. Our severity models analyze modifier genes and non-coding regions to predict disease progression and phenotypic expressivity.

Variable penetrance estimation.
Pharmacogenomic impact scores.
Longitudinal progression modeling.

[ MODEL OUTPUT ]

RISK TIER: MODERATE
Projected Onset: 45-50 yrs

The Core Engine

Built for precision and reproducibility.

Deep Sequencing

Analyzing methylation patterns and chromatin accessibility to contextualize gene regulation beyond standard exome sequencing.

{ Proteomics }

Structural Impact

Utilizing AlphaFold-derived predictions to assess how specific amino acid substitutions alter protein stability and function.

[ Bayesian_AI ]

Probabilistic Calling

Our variant caller significantly reduces false positives by weighing population frequency against phenotype specificity.

Data Sovereignty

Data is processed locally within region-specific enclaves to ensure compliance with national health data laws.

GDPR READY

Encryption Standards

AES-256 encryption at rest and TLS 1.3 in transit. We utilize zero-trust architecture for all API endpoints.

ISO 27001 (PENDING)

Clinical Validation

Algorithms are benchmarked against ClinVar and HGMD datasets. Whitepapers available upon request.

VALIDATION: IN PROCESS

Interpreting the complexity of Human Biology.